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If you need to work with Visio files without a full, permanent installation, consider these official (and safer) options:

Support for Visio 2010 officially ended on October 13, 2020 . download microsoft visio 2010 portable best

Microsoft has never released an official "portable" version of Visio 2010 for individual consumers. While some enterprise deployment tools allow for specialized "portable" setups for volume license holders, most files found online labeled as "Visio 2010 Portable" are unofficial modifications. Why Downloading Visio 2010 Today is Difficult If you need to work with Visio files